The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 37: 3-oxoacyl-[acyl-carrier-protein] reductase FabG

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
440 A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS)
(430 more)
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
415 O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS)
(405 more)
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
146 P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA)
(136 more)
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
146 P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP)
(136 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
146 P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA)
(136 more)
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
146 P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA)
(136 more)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
320 O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS) O54438 (/ISS)
(310 more)
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
241 P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP) P0A2C9 (/IMP)
(231 more)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
146 P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP)
(136 more)
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
146 P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP)
(136 more)
Biotin biosynthetic process GO:0009102
The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
146 P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP) P0AEK2 (/IMP)
(136 more)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
27 A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS) A0A1S0QWK0 (/ISS)
(17 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
146 P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA) P0AEK2 (/IDA)
(136 more)