The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 334: Inositol-3-phosphate synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
5 | P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
2 | Q38AQ2 (/EXP) Q38AQ2 (/EXP) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
2 | P42800 (/IGI) P42800 (/IGI) |
|
Inositol-3-phosphate synthase activity GO:0004512
Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
|
2 | P42800 (/ISS) P42800 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
7 | P11986 (/IMP) P11986 (/IMP) P11986 (/IMP) P11986 (/IMP) P11986 (/IMP) P42800 (/IMP) P42800 (/IMP) |
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
5 | P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) |
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
2 | P42800 (/IGI) P42800 (/IGI) |
|
Inositol biosynthetic process GO:0006021
The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
|
2 | P42800 (/ISS) P42800 (/ISS) |
|
GPI anchor biosynthetic process GO:0006506
The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
|
2 | Q38AQ2 (/IMP) Q38AQ2 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) P11986 (/IDA) Q38AQ2 (/IDA) Q38AQ2 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P11986 (/HDA) P11986 (/HDA) P11986 (/HDA) P11986 (/HDA) P11986 (/HDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P42800 (/IDA) P42800 (/IDA) |
|
Hyphal cell wall GO:0030446
The cell wall surrounding a fungal hypha.
|
2 | P42800 (/IDA) P42800 (/IDA) |