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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 311: Ornithine cyclodeaminase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1-pyrroline-2-carboxylate reductase (NAD(P)H). [EC: 1.5.1.49]
L-proline + NAD(P)(+) = 1-pyrroline-2-carboxylate + NAD(P)H.
  • The enzyme from the bacterium Colwellia psychrerythraea is involved in trans-3-hydroxy-L-proline metabolism.
  • In contrast to EC 1.5.1.1 which shows similar activity with 1-piperideine-2-carboxylate and 1-pyrroline-2-carboxylate, this enzyme is specific for the latter.
  • While the enzyme is active with both NADH and NADPH, activity is higher with NADPH.
 17 A0A150EKR5 A0A150EKR5 A0A150EKR5 A0A1J9YE88 A0A1J9YE88 A0A1J9YE88 A0A2S9HF83 A0A2S9HF83 C2SWY9 C2SWY9
(7 more...)
Alanine dehydrogenase. [EC: 1.4.1.1]
L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.
    		 9 A0A075WE43 A0A075WE43 A0A075WE43 A0A101DYW6 A0A101DYW6 A0A101DYW6 O28608 O28608 O28608