The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 262: 3 beta-hydroxysteroid dehydrogenase type 7 isoform...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854
Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).
|
1 | Q9H2F3 (/NAS) |
|
3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854
Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).
|
1 | Q9H2F3 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9H2F3 (/IPI) |
|
Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity GO:0047016
Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
|
1 | O35048 (/IDA) |
|
Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity GO:0047016
Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
|
1 | Q9EQC1 (/IMP) |
|
Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity GO:0047016
Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
|
1 | Q9EQC1 (/ISO) |
|
Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity GO:0047016
Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
|
1 | Q9H2F3 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
B cell chemotaxis GO:0035754
The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | O35048 (/ISS) Q9H2F3 (/ISS) |
|
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
|
1 | O35048 (/IDA) |
|
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
|
1 | Q9EQC1 (/ISO) |
|
Bile acid biosynthetic process GO:0006699
The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
|
1 | Q9H2F3 (/TAS) |
|
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
1 | O35048 (/IDA) |
|
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
1 | Q9EQC1 (/ISO) |
|
Bile acid metabolic process GO:0008206
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
|
1 | O35048 (/TAS) |
|
B cell chemotaxis GO:0035754
The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
1 | Q9EQC1 (/IMP) |
|
Liver regeneration GO:0097421
The regrowth of lost or destroyed liver.
|
1 | O35048 (/IEP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q9H2F3 (/TAS) |
|
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
|
1 | Q9H2F3 (/IDA) |
|
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
|
1 | Q9EQC1 (/ISO) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | O35048 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q9EQC1 (/ISO) |