The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 177: Retinol dehydrogenase 10

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Retinol dehydrogenase activity GO:0004745
Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
46 Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA)
(36 more)
Retinol dehydrogenase activity GO:0004745
Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
1 Q8VCH7 (/IMP)
Retinol dehydrogenase activity GO:0004745
Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
1 Q8VCH7 (/ISO)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
46 Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS)
(36 more)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
46 Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA)
(36 more)
Retinol metabolic process GO:0042572
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
46 Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA)
(36 more)
Retinal metabolic process GO:0042574
The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
46 Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA)
(36 more)
Retinoic acid biosynthetic process GO:0002138
The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.
2 A1L1W4 (/IMP) Q8VCH7 (/IMP)
Metanephros development GO:0001656
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
1 Q8VCH7 (/IMP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q8VCH7 (/IMP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 Q8VCH7 (/ISO)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
1 Q8VCH7 (/IMP)
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 Q8VCH7 (/IMP)
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 Q8VCH7 (/IMP)
Embryonic camera-type eye development GO:0031076
The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
1 Q8VCH7 (/IMP)
Embryonic forelimb morphogenesis GO:0035115
The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
1 Q8VCH7 (/IMP)
Retinol metabolic process GO:0042572
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
1 Q8VCH7 (/ISO)
Retinal metabolic process GO:0042574
The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
1 Q8VCH7 (/ISO)
Ear development GO:0043583
The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
1 Q8VCH7 (/IMP)
Nose development GO:0043584
The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).
1 Q8VCH7 (/IMP)
Embryonic organ development GO:0048568
Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 Q8VCH7 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
1 Q8VCH7 (/IMP)
Primary lung bud formation GO:0060431
The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.
1 Q8VCH7 (/IMP)
Bud elongation involved in lung branching GO:0060449
The process in which a bud in the lung grows out from the point where it is formed.
1 Q8VCH7 (/IMP)
Positive regulation of retinoic acid biosynthetic process GO:1900054
Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.
1 Q80ZF7 (/IMP)
Positive regulation of retinoic acid biosynthetic process GO:1900054
Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.
1 Q8VCH7 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
46 Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA)
(36 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
46 Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS) Q8IZV5 (/TAS)
(36 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
46 Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA) Q8IZV5 (/IDA)
(36 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8VCH7 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8VCH7 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8VCH7 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q80ZF7 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q8VCH7 (/ISO)