The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"HUPs
".
FunFam 36: Glutamine-dependent NAD(+) synthetase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
NAD+ synthase (glutamine-hydrolyzing) activity GO:0003952
Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
|
4 | P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) |
|
NAD+ synthase (glutamine-hydrolyzing) activity GO:0003952
Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
|
4 | P38795 (/IMP) P38795 (/IMP) P38795 (/IMP) P38795 (/IMP) |
|
Glutaminase activity GO:0004359
Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
|
4 | P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) |
|
Glutaminase activity GO:0004359
Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
|
4 | P38795 (/IMP) P38795 (/IMP) P38795 (/IMP) P38795 (/IMP) |
|
NAD+ synthase (glutamine-hydrolyzing) activity GO:0003952
Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
|
2 | O74940 (/ISO) Q711T7 (/ISO) |
|
NAD+ synthase (glutamine-hydrolyzing) activity GO:0003952
Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
|
1 | Q5ALW6 (/ISA) |
|
NAD+ synthase (glutamine-hydrolyzing) activity GO:0003952
Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
|
1 | Q54ML1 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q6IA69 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | O74940 (/ISM) |
|
NAD+ synthase activity GO:0008795
Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.
|
1 | Q9XXK6 (/IMP) |
|
NAD+ synthase activity GO:0008795
Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.
|
1 | Q711T7 (/ISO) |
|
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
|
1 | Q54ML1 (/ISS) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
5 | P38795 (/IMP) P38795 (/IMP) P38795 (/IMP) P38795 (/IMP) Q9XXK6 (/IMP) |
|
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
4 | P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) |
|
NAD biosynthetic process GO:0009435
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
|
2 | O74940 (/ISO) Q711T7 (/ISO) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | Q9XXK6 (/IMP) |
|
Nicotinate nucleotide salvage GO:0019358
The generation of nicotinate nucleotide without de novo synthesis.
|
1 | Q5ALW6 (/ISA) |
|
NAD metabolic process GO:0019674
The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
|
1 | Q6IA69 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) P38795 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q6IA69 (/IDA) Q9C723 (/IDA) Q9C723 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O74940 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O74940 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q711T7 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q6IA69 (/TAS) |