The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 103: tyrosine--tRNA ligase 1, cytoplasmic

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tyrosine-tRNA ligase activity GO:0004831
Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+).
3 Q8IAR7 (/IDA) Q8IAR7 (/IDA) Q8IAR7 (/IDA)
Host cell surface receptor binding GO:0046789
Interacting selectively and non-covalently with a receptor on the host cell surface.
3 Q8IAR7 (/IDA) Q8IAR7 (/IDA) Q8IAR7 (/IDA)
Tyrosine-tRNA ligase activity GO:0004831
Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+).
1 Q551A1 (/ISS)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tyrosyl-tRNA aminoacylation GO:0006437
The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase.The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.T
4 Q551A1 (/ISS) Q8IAR7 (/ISS) Q8IAR7 (/ISS) Q8IAR7 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell cytosol GO:0044164
The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q8IAR7 (/IDA) Q8IAR7 (/IDA) Q8IAR7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q551A1 (/ISS)