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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 94: GTPase Era

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
 57 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(47 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
 57 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(47 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 56 P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI) P06616 (/IPI)
(46 more)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Small ribosomal subunit rRNA binding GO:0070181
Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
 9 A0A0F7RBV4 (/ISS) A0A0F7RBV4 (/ISS) Q9KPB3 (/ISS) Q9KPB3 (/ISS) Q9KPB3 (/ISS) Q9KPB3 (/ISS) Q9KPB3 (/ISS) Q9KPB3 (/ISS) Q9KPB3 (/ISS)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
 1 P37214 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Ribosomal small subunit biogenesis GO:0042274
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Ribosomal small subunit biogenesis GO:0042274
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
 56 P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI) P06616 (/IGI)
(46 more)
Ribosomal small subunit biogenesis GO:0042274
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
 56 P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP) P06616 (/IMP)
(46 more)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Negative regulation of DNA-dependent DNA replication initiation GO:0032297
Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.
 9 P42182 (/IDA) P42182 (/IDA) P42182 (/IDA) P42182 (/IDA) P42182 (/IDA) P42182 (/IDA) P42182 (/IDA) P42182 (/IDA) P42182 (/IDA)
Positive regulation of cell division GO:0051781
Any process that activates or increases the frequency, rate or extent of cell division.
 9 P42182 (/IMP) P42182 (/IMP) P42182 (/IMP) P42182 (/IMP) P42182 (/IMP) P42182 (/IMP) P42182 (/IMP) P42182 (/IMP) P42182 (/IMP)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
 4 B9FI63 (/ISS) B9FI63 (/ISS) Q8VZ74 (/ISS) Q8VZ74 (/ISS)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
 4 B9FI63 (/ISS) B9FI63 (/ISS) Q8VZ74 (/ISS) Q8VZ74 (/ISS)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
 1 K7UTH7 (/IMP)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
 1 K7UTH7 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 57 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(47 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 56 P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS) P06616 (/TAS)
(46 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Extrinsic component of cytoplasmic side of plasma membrane GO:0031234
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
 56 P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA) P06616 (/IDA)
(46 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 9 P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA) P9WNK9 (/HDA)
Chloroplast nucleoid GO:0042644
The region of a chloroplast to which the DNA is confined.
 4 B9FI63 (/ISS) B9FI63 (/ISS) Q8VZ74 (/ISS) Q8VZ74 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
 2 Q8VZ74 (/IDA) Q8VZ74 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 1 P37214 (/IDA)
Chloroplast nucleoid GO:0042644
The region of a chloroplast to which the DNA is confined.
 1 K7UTH7 (/IDA)