The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 826: Replicative DNA helicase Mcm

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
15 Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS)
(5 more)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
15 Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9UXG1 (/IPI) Q9UXG1 (/IPI) Q9UXG1 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 Q9UXG1 (/IPI) Q9UXG1 (/IPI) Q9UXG1 (/IPI)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA replication initiation GO:0006270
The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
15 Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS) Q8IDF0 (/ISS)
(5 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MCM complex GO:0042555
A hexameric protein complex required for the initiation and regulation of DNA replication.
1 Q54RU0 (/ISS)