The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 554: ADP-ribosylation factor 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
59 P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS) P61209 (/ISS)
(49 more)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Post-Golgi vesicle-mediated transport GO:0006892
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Male meiosis cytokinesis GO:0007112
A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
59 P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS)
(49 more)
Regulation of lipid storage GO:0010883
Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
59 P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA)
(49 more)
ARF protein signal transduction GO:0032011
A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.
59 P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI)
(49 more)
Golgi to plasma membrane protein transport GO:0043001
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
59 P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI)
(49 more)
Golgi to plasma membrane protein transport GO:0043001
The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Synaptic vesicle endocytosis GO:0048488
A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.
59 P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS) P61209 (/TAS)
(49 more)
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Positive regulation of neuron remodeling GO:1904801
Any process that activates or increases the frequency, rate or extent of neuron remodeling.
59 P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI) P61209 (/IGI)
(49 more)
Positive regulation of neuron remodeling GO:1904801
Any process that activates or increases the frequency, rate or extent of neuron remodeling.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)
Mitotic cleavage furrow ingression GO:1990386
Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
59 P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP) P61209 (/IMP)
(49 more)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
59 P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA)
(49 more)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
59 P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA)
(49 more)
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
59 P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA)
(49 more)
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
59 P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA)
(49 more)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
59 P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA) P61209 (/IDA)
(49 more)