The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 497: Atlastin-1 isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
20 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(10 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
16 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(6 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
15 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(5 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q6PST4 (/IPI) Q8BH66 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
6 Q6PST4 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
5 Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
5 Q8WXF7 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI) Q8WXF7 (/IPI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q8BH66 (/ISO)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 Q6PST4 (/IMP)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 Q8BH66 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8BH66 (/ISO)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
20 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(10 more)
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
16 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(6 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
16 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(6 more)
Endoplasmic reticulum tubular network membrane organization GO:1990809
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.
16 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(6 more)
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
5 Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
5 Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Endoplasmic reticulum tubular network membrane organization GO:1990809
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.
5 Q8WXF7 (/IMP) Q8WXF7 (/IMP) Q8WXF7 (/IMP) Q8WXF7 (/IMP) Q8WXF7 (/IMP)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 B8A6H1 (/IDA) E9QGX9 (/IDA)
Determination of dorsal identity GO:0048263
Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
2 B8A6H1 (/IDA) E9QGX9 (/IDA)
Determination of dorsal identity GO:0048263
Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
2 B8A6H1 (/IGI) E9QGX9 (/IGI)
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
1 Q8BH66 (/ISO)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
1 Q6PST4 (/IMP)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
1 Q8BH66 (/ISO)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q8BH66 (/ISO)
Endoplasmic reticulum tubular network membrane organization GO:1990809
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.
1 Q8BH66 (/ISO)

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi cis cisterna GO:0000137
The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
20 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(10 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
20 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(10 more)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
20 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(10 more)
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
20 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(10 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
16 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(6 more)
Endoplasmic reticulum tubular network membrane GO:0098826
The membrane of the endoplasmic reticulum tubular network.
16 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(6 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
15 Q58D72 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q5R4P1 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS) Q60HD2 (/ISS)
(5 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
6 Q6PST4 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Endoplasmic reticulum tubular network membrane GO:0098826
The membrane of the endoplasmic reticulum tubular network.
5 Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA) Q8WXF7 (/IDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2 B8A6H1 (/IDA) E9QGX9 (/IDA)
Golgi cis cisterna GO:0000137
The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
1 Q6PST4 (/IDA)
Golgi cis cisterna GO:0000137
The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
1 Q8BH66 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BH66 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q8BH66 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q6PST4 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q8BH66 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q6PST4 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q8BH66 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8BH66 (/ISO)
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
1 Q8BH66 (/IDA)
Endoplasmic reticulum tubular network membrane GO:0098826
The membrane of the endoplasmic reticulum tubular network.
1 Q8BH66 (/ISO)