The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 440: Ras-related protein Rab-30

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
63 Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS)
(53 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
3 Q9VM50 (/ISS) Q9VM50 (/ISS) Q9VM50 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9VM50 (/IPI) Q9VM50 (/IPI) Q9VM50 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
126 Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS)
(116 more)
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
63 Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP) Q15771 (/IMP)
(53 more)
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
63 Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO)
(53 more)
Germ-band shortening GO:0007390
The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
3 Q9VM50 (/IMP) Q9VM50 (/IMP) Q9VM50 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
3 Q9VM50 (/IMP) Q9VM50 (/IMP) Q9VM50 (/IMP)
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
3 Q9VM50 (/IMP) Q9VM50 (/IMP) Q9VM50 (/IMP)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
3 Q9VM50 (/ISS) Q9VM50 (/ISS) Q9VM50 (/ISS)
Rab protein signal transduction GO:0032482
A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
3 Q9VM50 (/ISS) Q9VM50 (/ISS) Q9VM50 (/ISS)
Imaginal disc fusion, thorax closure GO:0046529
The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
3 Q9VM50 (/IMP) Q9VM50 (/IMP) Q9VM50 (/IMP)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
129 A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA) A8K5R1 (/IDA)
(119 more)
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
126 Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS)
(116 more)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
126 Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS)
(116 more)
Golgi cisterna GO:0031985
Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.
126 Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS) Q17QB7 (/ISS)
(116 more)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
66 Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA)
(56 more)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
63 Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS)
(53 more)
Golgi stack GO:0005795
The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
63 Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS) Q15771 (/TAS)
(53 more)
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
63 Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA)
(53 more)
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
63 Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO)
(53 more)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
63 Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO)
(53 more)
Golgi cisterna GO:0031985
Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.
63 Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA) Q15771 (/IDA)
(53 more)
Golgi cisterna GO:0031985
Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.
63 Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO)
(53 more)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
63 Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO) Q923S9 (/ISO)
(53 more)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
3 Q9VM50 (/IDA) Q9VM50 (/IDA) Q9VM50 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
3 Q9VM50 (/IDA) Q9VM50 (/IDA) Q9VM50 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
3 Q9VM50 (/IDA) Q9VM50 (/IDA) Q9VM50 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
3 Q9VM50 (/ISS) Q9VM50 (/ISS) Q9VM50 (/ISS)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
3 Q9VM50 (/IDA) Q9VM50 (/IDA) Q9VM50 (/IDA)