The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 430: Probable Ras-related protein Rab-18

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
29 P35293 (/ISS) P35293 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q5EB77 (/ISS) Q5R5H5 (/ISS)
(19 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
19 Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS)
(9 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI) Q9NP72 (/IPI)
(9 more)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
19 Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA)
(9 more)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
2 P35293 (/ISO) P35293 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
48 P35293 (/ISS) P35293 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q5EB77 (/ISS) Q5R5H5 (/ISS)
(38 more)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
48 P35293 (/ISS) P35293 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q0IIG8 (/ISS) Q5EB77 (/ISS) Q5R5H5 (/ISS)
(38 more)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
19 Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS) Q9NP72 (/NAS)
(9 more)
Lipid droplet organization GO:0034389
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
19 Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP)
(9 more)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
19 Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS)
(9 more)
Endoplasmic reticulum tubular network organization GO:0071786
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.
19 Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP) Q9NP72 (/IMP)
(9 more)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
2 Q6DHC1 (/IMP) Q6P129 (/IMP)
Lipid droplet organization GO:0034389
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
2 P35293 (/ISO) P35293 (/ISO)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
2 Q6DHC1 (/IMP) Q6P129 (/IMP)
Import into nucleus GO:0051170
The directed movement of substances into the nucleus.
2 P35293 (/IMP) P35293 (/IMP)
Endoplasmic reticulum tubular network organization GO:0071786
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.
2 P35293 (/ISO) P35293 (/ISO)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 Q6DHC1 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
19 Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA)
(9 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
19 Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS)
(9 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
19 Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS)
(9 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
19 Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS)
(9 more)
Secretory granule membrane GO:0030667
The lipid bilayer surrounding a secretory granule.
19 Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS) Q9NP72 (/TAS)
(9 more)
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
19 Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA) Q9NP72 (/IDA)
(9 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
2 P35293 (/ISO) P35293 (/ISO)
Endoplasmic reticulum tubular network GO:0071782
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
2 P35293 (/ISO) P35293 (/ISO)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q5EB77 (/EXP)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q5EB77 (/IDA)