The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 391: ATP-dependent DNA helicase RecG

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
33 P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA)
(23 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
23 P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI) P24230 (/IPI)
(13 more)
Four-way junction helicase activity GO:0009378
Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
10 Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
10 Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA) Q9HTL3 (/IDA)
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
7 Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS)
Four-way junction helicase activity GO:0009378
Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
7 Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
23 P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP) P24230 (/IMP)
(13 more)
DNA duplex unwinding GO:0032508
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
23 P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA)
(13 more)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
11 F4INA9 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP)
(1 more)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
10 Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
10 Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP)
Cellular response to chromate GO:0071247
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.
10 Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP)
Cellular response to selenite ion GO:0072715
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.
10 Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP) Q9HTL3 (/IMP)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
7 Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
7 Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS) Q9KNM1 (/ISS)
Mitochondrial DNA inheritance GO:0033955
The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.
1 F4INA9 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
23 P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA)
(13 more)
Holliday junction helicase complex GO:0009379
A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.
23 P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA) P24230 (/IDA)
(13 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P9WMQ7 (/HDA) P9WMQ7 (/HDA) P9WMQ7 (/HDA) P9WMQ7 (/HDA) P9WMQ7 (/HDA) P9WMQ7 (/HDA) P9WMQ7 (/HDA) P9WMQ7 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 F4INA9 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 F4INA9 (/IDA)