The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 378: ATP-dependent Clp protease ATP-binding subunit clp...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
3 | A0A0B4LID7 (/ISS) Q960M5 (/ISS) Q9VDS7 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | O76031 (/IPI) O76031 (/IPI) Q9JHS4 (/IPI) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
3 | O76031 (/IDA) O76031 (/IDA) Q9JHS4 (/IDA) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | O76031 (/ISS) O76031 (/ISS) |
|
Peptidase activator activity GO:0016504
Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
2 | O76031 (/ISS) O76031 (/ISS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9JHS4 (/IDA) |
|
Peptidase activator activity GO:0016504
Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
|
1 | Q9JHS4 (/ISO) |
|
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q9JHS4 (/ISO) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
|
3 | A0A0B4LID7 (/ISS) Q960M5 (/ISS) Q9VDS7 (/ISS) |
|
Proteolysis involved in cellular protein catabolic process GO:0051603
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
|
3 | Q5R7N3 (/ISS) Q5U2U0 (/ISS) Q9JHS4 (/ISS) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
|
2 | A0A0G2KJF1 (/IMP) Q66HW5 (/IMP) |
|
Proteolysis involved in cellular protein catabolic process GO:0051603
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9JHS4 (/ISO) |
|
Proteolysis involved in cellular protein catabolic process GO:0051603
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
|
1 | Q9JHS4 (/ISO) |
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
5 | A0A024R5X7 (/IDA) A0A024R5X7 (/IDA) O76031 (/IDA) O76031 (/IDA) Q9JHS4 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | A0A024R5X7 (/IDA) A0A024R5X7 (/IDA) O76031 (/IDA) O76031 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A0A024R5X7 (/IDA) A0A024R5X7 (/IDA) O76031 (/IDA) O76031 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | A0A0B4LID7 (/ISS) Q960M5 (/ISS) Q9VDS7 (/ISS) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
3 | Q5R7N3 (/ISS) Q5U2U0 (/ISS) Q9JHS4 (/ISS) |
|
Endopeptidase Clp complex GO:0009368
A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
|
3 | Q5R7N3 (/ISS) Q5U2U0 (/ISS) Q9JHS4 (/ISS) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | O76031 (/ISS) O76031 (/ISS) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
Endopeptidase Clp complex GO:0009368
A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
Mitochondrial endopeptidase Clp complex GO:0009841
A Clp endopeptidase complex located in the mitochondrion.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
|
2 | O76031 (/IDA) O76031 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9JHS4 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9JHS4 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9JHS4 (/ISO) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q9JHS4 (/HDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q9JHS4 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9JHS4 (/ISO) |
|
Endopeptidase Clp complex GO:0009368
A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
|
1 | Q9JHS4 (/ISO) |
|
Mitochondrial endopeptidase Clp complex GO:0009841
A Clp endopeptidase complex located in the mitochondrion.
|
1 | Q9JHS4 (/ISO) |
|
Mitochondrial nucleoid GO:0042645
The region of a mitochondrion to which the DNA is confined.
|
1 | Q9JHS4 (/ISO) |