The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 372: Adenylate kinase isoenzyme 6 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
21 Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q7JYV7 (/IDA) Q9FJI1 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA)
(11 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 Q9FJI1 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI) Q9Y3D8 (/IPI)
(4 more)
Nucleoside monophosphate kinase activity GO:0050145
Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.
13 Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS)
(3 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
6 Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
4 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO) Q8VCP8 (/ISO)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
4 A5PJA1 (/ISS) Q5EB68 (/ISS) Q8VCP8 (/ISS) Q9TTU2 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
RRNA primary transcript binding GO:0042134
Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q8TG40 (/IDA)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
13 Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS)
(3 more)
Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
6 Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
6 Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Maturation of SSU-rRNA GO:0030490
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q54Y03 (/ISS)
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
1 Q9FJI1 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q8TG40 (/IMP)
Maturation of SSU-rRNA GO:0030490
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
1 Q54Y03 (/ISS)
Phenotypic switching GO:0036166
A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
1 Q8TG40 (/IMP)
Nucleotide phosphorylation GO:0046939
The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside.
1 Q9FJI1 (/IDA)
Developmental vegetative growth GO:0080186
The increase in size or mass of non-reproductive plant parts.
1 Q9FJI1 (/IMP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
26 D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA)
(16 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
26 D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA) D6RDH4 (/IDA)
(16 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
13 Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS) Q9Y3D8 (/TAS)
(3 more)
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
13 Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA) Q9Y3D8 (/IDA)
(3 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
13 Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA) Q9Y3D8 (/HDA)
(3 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q584W4 (/IDA) Q584W4 (/IDA) Q7JYV7 (/IDA) Q9FJI1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP) Q12055 (/IMP)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
6 Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA) Q12055 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 A5PJA1 (/ISS) Q5EB68 (/ISS) Q8VCP8 (/ISS) Q9TTU2 (/ISS)
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
4 A5PJA1 (/ISS) Q5EB68 (/ISS) Q8VCP8 (/ISS) Q9TTU2 (/ISS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
3 Q4Q7A6 (/ISO) Q584W4 (/ISO) Q584W4 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8VCP8 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8VCP8 (/ISO)
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
1 Q8VCP8 (/ISO)