The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 330: Septum-promoting GTP-binding protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
9 P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P87027 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P38987 (/IPI) P38987 (/IPI) P38987 (/IPI) P38987 (/IPI) P38987 (/IPI) P38987 (/IPI) P38987 (/IPI) P38987 (/IPI) P87027 (/IPI)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
8 P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 A0A1D8PCX9 (/IGI) A0A1D8PCX9 (/IGI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q54EY3 (/ISS)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
1 P87027 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of exit from mitosis GO:0031536
Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
8 P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP)
Mitotic spindle orientation checkpoint GO:0031578
A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.
8 P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP)
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
8 P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP)
Regulation of protein localization to mitotic spindle pole body GO:1902542
Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.
8 P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP)
Negative regulation of protein localization to nucleolus GO:1904750
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.
8 P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP) P38987 (/IMP)
Exit from mitosis GO:0010458
The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2 A0A1D8PCX9 (/IMP) A0A1D8PCX9 (/IMP)
Septation initiation signaling GO:0031028
The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.
1 P87027 (/IGI)
Cellular protein localization GO:0034613
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
1 P87027 (/IMP)
Positive regulation of mitotic division septum assembly GO:0140281
Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
1 P87027 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
8 P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA) P38987 (/IDA)
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
3 A0A1D8PCX9 (/IDA) A0A1D8PCX9 (/IDA) P87027 (/IDA)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
2 A0A1D8PCX9 (/IGI) A0A1D8PCX9 (/IGI)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 Q54EY3 (/IDA)
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
1 P87027 (/HDA)