The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 243: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
17 O43252 (/ISS) O43252 (/ISS) O43252 (/ISS) O54820 (/ISS) O88428 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS)
(7 more)
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
17 O43252 (/ISS) O43252 (/ISS) O43252 (/ISS) O54820 (/ISS) O88428 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS) O95340 (/ISS)
(7 more)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
6 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) O88428 (/IDA) Q22501 (/IDA) Q60967 (/IDA)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
6 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) O88428 (/IDA) Q22501 (/IDA) Q60967 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 O43252 (/IPI) O43252 (/IPI) O43252 (/IPI)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
1 Q27128 (/IGI)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
1 Q60967 (/ISO)
Adenylylsulfate kinase activity GO:0004020
Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
1 O54820 (/ISS)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
1 Q27128 (/IGI)
Sulfate adenylyltransferase (ATP) activity GO:0004781
Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
1 Q60967 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q27128 (/NAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q60967 (/ISO)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
8 O43252 (/TAS) O43252 (/TAS) O43252 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
8 O43252 (/TAS) O43252 (/TAS) O43252 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
5 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) Q22501 (/IDA) Q60967 (/IDA)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
4 O43252 (/IDA) O43252 (/IDA) O43252 (/IDA) O88428 (/IDA)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
2 O54820 (/ISS) Q60967 (/ISS)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
1 Q27128 (/IGI)
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
1 Q60967 (/ISO)
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
1 O88428 (/IMP)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
1 Q60967 (/ISO)
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process GO:0050428
The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
1 O54820 (/ISS)
Bone development GO:0060348
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
1 O88428 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 B2RYI8 (/TAS) B5DFH4 (/TAS) O43252 (/TAS) O43252 (/TAS) O43252 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS) O95340 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 Q7KUT8 (/HDA) Q8IQV1 (/HDA) Q961A8 (/HDA) Q9VW48 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q22501 (/IDA)
Sulfate adenylyltransferase complex (ATP) GO:0009336
An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.
1 Q60967 (/IC)