The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 126: Galactose/methyl galactoside import ATP-binding pr...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
124 P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM) P04983 (/ISM)
(114 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
105 P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI) P04983 (/IPI)
(95 more)
ATPase-coupled monosaccharide transmembrane transporter activity GO:0015407
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.
55 P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA)
(45 more)
D-ribose transmembrane transporter activity GO:0015591
Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
55 P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA)
(45 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
50 P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM) P0AAF3 (/ISM)
(40 more)
Galactose transmembrane transporter activity GO:0005354
Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
49 P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP)
(39 more)
Methylgalactoside transmembrane transporter activity GO:0015592
Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
49 P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP)
(39 more)
D-ribose-importing ATPase activity GO:0015611
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).
26 Q48JT2 (/ISS) Q48JT2 (/ISS) Q48JT2 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS)
(16 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
13 Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS)
(3 more)
D-xylose transmembrane transporter activity GO:0015148
Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.
3 P37388 (/IMP) P37388 (/IMP) P37388 (/IMP)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
D-ribose transmembrane transport GO:0015752
The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
55 P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP) P04983 (/IMP)
(45 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
49 P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP) P0AAG8 (/IEP)
(39 more)
Galactose transmembrane transport GO:0015757
The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
49 P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP)
(39 more)
Methylgalactoside transport GO:0015765
The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
49 P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP) P0AAG8 (/IMP)
(39 more)
D-ribose transmembrane transport GO:0015752
The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
26 Q48JT2 (/ISS) Q48JT2 (/ISS) Q48JT2 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS) Q81V36 (/ISS)
(16 more)
D-xylose transmembrane transport GO:0015753
The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.
3 P37388 (/IMP) P37388 (/IMP) P37388 (/IMP)
D-xylose metabolic process GO:0042732
The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.
3 P37388 (/IMP) P37388 (/IMP) P37388 (/IMP)
L-arabinose transmembrane transport GO:0042882
The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.
3 Q1JUP7 (/IGC) Q1JUP7 (/IGC) Q1JUP7 (/IGC)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
116 P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA)
(106 more)
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
55 P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA) P04983 (/IDA)
(45 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
50 P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA) P0AAF3 (/IDA)
(40 more)