The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1142: RecBCD enzyme subunit RecB

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
Endodeoxyribonuclease activity GO:0004520
Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P08394 (/IPI) P08394 (/IPI) P08394 (/IPI) P08394 (/IPI) P08394 (/IPI) P08394 (/IPI) P08394 (/IPI) P08394 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
DNA-dependent ATPase activity GO:0008094
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
Exodeoxyribonuclease V activity GO:0008854
Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
DNA translocase activity GO:0015616
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
Exodeoxyribonuclease V activity GO:0008854
Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.
7 Q8EF45 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Double-strand break repair via homologous recombination GO:0000724
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
8 P08394 (/TAS) P08394 (/TAS) P08394 (/TAS) P08394 (/TAS) P08394 (/TAS) P08394 (/TAS) P08394 (/TAS) P08394 (/TAS)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
8 P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
8 P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP)
Clearance of foreign intracellular DNA GO:0044355
A defense process that protects an organism from invading foreign DNA.
8 P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP) P08394 (/IMP)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
7 Q8EF45 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exodeoxyribonuclease V complex GO:0009338
An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.
8 P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA) P08394 (/IDA)
Exodeoxyribonuclease V complex GO:0009338
An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.
7 Q8EF45 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS) Q9KPP6 (/ISS)