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CATH Superfamily 3.40.50.261

Succinyl-CoA synthetase domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Succinyl-CoA synthetase domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinate--CoA ligase (ADP-forming). [EC: 6.2.1.5]
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.
    		 1941 A0A009FWG7 A0A009IVG6 A0A009JNH0 A0A009QKM1 A0A009RP50 A0A009SF98 A0A009TAP0 A0A010JHZ1 A0A010L7D5 A0A011SX21
    (1931 more...)
    ATP citrate synthase. [EC: 2.3.3.8]
    ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
    • The enzyme can be dissociated into components, two of which are identical with EC 4.1.3.34 and EC 6.2.1.18.
    • Formerly EC 4.1.3.8.
    		 38 A0A024R1T9 A0A024R1T9 A0A0B0EBS3 A0A0E0MV51 A0A178UM28 A0A178V742 A0A178W4V2 A0A2I2ZLM6 A0A2I2ZLM6 A2WNV6
    (28 more...)
    Succinate--CoA ligase (GDP-forming). [EC: 6.2.1.4]
    GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
    • Itaconate can act instead of succinate and ITP instead of GTP.
    		 24 A0A024R325 A0A1W4W4Q4 A0A3P4AQT9 A0A480VSG5 B4QPY9 F6DEK7 O19069 P09143 P13086 P25126
    (14 more...)
    Malate--CoA ligase. [EC: 6.2.1.9]
    ATP + malate + CoA = ADP + phosphate + malyl-CoA.
      		 21 A0A0Q4VXR2 A0A0Q4WCK8 A0A0Q5CL84 A0A0X1SGD6 A0A0X1SGE2 A0A1A5HN00 A0A1S1P402 A0A1S1P988 A0A1W6RL53 A0A1W6RLA1
      (11 more...)
      Acetate--CoA ligase (ADP-forming). [EC: 6.2.1.13]
      ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.
      • Also acts on propanoate and, very slowly, on butanoate.
      		 16 A0A075WGK8 A0A075WGK8 E7FI45 E7FI45 I6U612 I6U612 I6U8C5 I6U8C5 O28341 O28341
      (6 more...)