The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 217: Piwi like RNA-mediated gene silencing 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
PiRNA binding GO:0034584
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
3 | Q7Z3Z4 (/IDA) Q7Z3Z4 (/IDA) Q8CGT6 (/IDA) |
|
PiRNA binding GO:0034584
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8CGT6 (/IPI) |
|
PiRNA binding GO:0034584
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
1 | Q8CGT6 (/ISO) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
Gene silencing by RNA GO:0031047
Any process in which RNA molecules inactivate expression of target genes.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
|
2 | Q7Z3Z4 (/IMP) Q7Z3Z4 (/IMP) |
|
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
|
2 | Q4G033 (/ISS) Q8CGT6 (/ISS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q8CGT6 (/IMP) |
|
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
1 | Q8CGT6 (/IMP) |
|
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
|
1 | Q8CGT6 (/ISO) |
|
Gene silencing by RNA GO:0031047
Any process in which RNA molecules inactivate expression of target genes.
|
1 | Q8CGT6 (/IMP) |
|
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
1 | Q8CGT6 (/IDA) |
|
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
1 | Q8CGT6 (/IMP) |
|
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
|
1 | Q8CGT6 (/IMP) |
|
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
1 | Q4G033 (/IMP) |
|
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
1 | Q8CGT6 (/ISO) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q7Z3Z4 (/IDA) Q7Z3Z4 (/IDA) Q8CGT6 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q7Z3Z4 (/IDA) Q7Z3Z4 (/IDA) Q8CGT6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
PiP-body GO:0071547
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
|
3 | Q4G033 (/ISS) Q7Z3Z4 (/ISS) Q7Z3Z4 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8CGT6 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8CGT6 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8CGT6 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8CGT6 (/TAS) |
|
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
|
1 | Q8CGT6 (/IDA) |
|
PiP-body GO:0071547
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
|
1 | Q8CGT6 (/IDA) |