The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 2: DNA-binding response regulator PhoP
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
37 |
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
(27 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
37 |
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
(27 more) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
31 |
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
(21 more) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
31 |
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
(21 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
31 |
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
(21 more) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
13 |
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
(3 more) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
7 | Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) Q9I2U3 (/IMP) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
6 | I3NI96 (/IDA) I3NI96 (/IDA) I3NI96 (/IDA) I3NI96 (/IDA) I3NI96 (/IDA) I3NI96 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
6 | I3NI96 (/IPI) I3NI96 (/IPI) I3NI96 (/IPI) I3NI96 (/IPI) I3NI96 (/IPI) I3NI96 (/IPI) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
5 | O07776 (/IDA) O07776 (/IDA) O07776 (/IDA) O07776 (/IDA) O07776 (/IDA) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
2 | Q04803 (/IDA) Q04803 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
31 |
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
P23836 (/EXP)
(21 more) |
|
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
|
18 |
Q9I2U3 (/IMP)
Q9I2U3 (/IMP)
Q9I2U3 (/IMP)
Q9I2U3 (/IMP)
Q9I2U3 (/IMP)
Q9I2U3 (/IMP)
Q9I2U3 (/IMP)
Q9I4F9 (/IMP)
Q9I4F9 (/IMP)
Q9I4F9 (/IMP)
(8 more) |
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
13 |
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KKK0 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
Q9KSD8 (/ISS)
(3 more) |
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
8 | Q04803 (/IDA) Q04803 (/IDA) Q9HV32 (/IDA) Q9HV32 (/IDA) Q9HV32 (/IDA) Q9HV32 (/IDA) Q9HV32 (/IDA) Q9HV32 (/IDA) |
|
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
|
6 | Q9I529 (/EXP) Q9I529 (/EXP) Q9I529 (/EXP) Q9I529 (/EXP) Q9I529 (/EXP) Q9I529 (/EXP) |
|
Negative regulation of phosphorelay signal transduction system GO:0070298
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
|
5 | O07776 (/IDA) O07776 (/IDA) O07776 (/IDA) O07776 (/IDA) O07776 (/IDA) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
2 | P52076 (/EXP) P52076 (/EXP) |
|
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
|
2 | P52076 (/IMP) P52076 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
37 |
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
I3NI96 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
(27 more) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
37 |
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
I3NI96 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
P23836 (/IPI)
(27 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
31 |
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
P23836 (/IDA)
(21 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | O07776 (/HDA) O07776 (/HDA) O07776 (/HDA) O07776 (/HDA) O07776 (/HDA) |