The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 146: Putative two-component response regulator SSK1p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
4 Q07084 (/IMP) Q07084 (/IMP) Q07084 (/IMP) Q5AKU6 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P87323 (/IPI) Q07084 (/IPI) Q07084 (/IPI) Q07084 (/IPI)
Protein kinase activator activity GO:0030295
Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
3 Q07084 (/IDA) Q07084 (/IDA) Q07084 (/IDA)
Protein kinase activator activity GO:0030295
Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
3 Q07084 (/IMP) Q07084 (/IMP) Q07084 (/IMP)
Mitogen-activated protein kinase kinase kinase binding GO:0031435
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
3 Q07084 (/IPI) Q07084 (/IPI) Q07084 (/IPI)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
1 P87323 (/IPI)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
1 Q5AKU6 (/ISS)

There are 37 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
4 P87323 (/IMP) Q5AKU6 (/IMP) Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Activation of MAPKKK activity GO:0000185
Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
3 Q07084 (/IDA) Q07084 (/IDA) Q07084 (/IDA)
Activation of MAPKKK activity GO:0000185
Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
3 Q07084 (/IGI) Q07084 (/IGI) Q07084 (/IGI)
Activation of MAPKKK activity GO:0000185
Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
3 Q07084 (/IMP) Q07084 (/IMP) Q07084 (/IMP)
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
3 Q07084 (/IDA) Q07084 (/IDA) Q07084 (/IDA)
Positive regulation of protein autophosphorylation GO:0031954
Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
3 Q07084 (/IDA) Q07084 (/IDA) Q07084 (/IDA)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
3 Q5AKU6 (/IMP) Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
3 Q07084 (/IMP) Q07084 (/IMP) Q07084 (/IMP)
Osmosensory signaling pathway GO:0007231
The series of molecular signals initiated in response to osmotic change.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
2 Q5AVI3 (/IGI) Q5AVI3 (/IGI)
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
2 Q5AVI3 (/ISA) Q5AVI3 (/ISA)
Conidium formation GO:0048315
The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Cellular hyperosmotic response GO:0071474
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Cellular hyperosmotic salinity response GO:0071475
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Regulation of conidium formation GO:0075306
Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
2 Q5AVI3 (/IMP) Q5AVI3 (/IMP)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
1 P87323 (/IDA)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
1 P87323 (/IMP)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
1 Q5AKU6 (/ISS)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 Q5AKU6 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q5AKU6 (/IMP)
Evasion or tolerance of host immune response GO:0020012
Any process, either active or passive, by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q5AKU6 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q5AKU6 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
1 Q5AKU6 (/IMP)
Positive regulation of stress-activated MAPK cascade GO:0032874
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
1 P87323 (/IGI)
Positive regulation of stress-activated MAPK cascade GO:0032874
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
1 P87323 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P87323 (/IC)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 Q5AKU6 (/IMP)
Filamentous growth of a population of unicellular organisms in response to neutral pH GO:0036178
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
1 Q5AKU6 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 Q5AKU6 (/IMP)
Cellular response to neutral pH GO:0036244
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
1 Q5AKU6 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q5AKU6 (/IMP)
Regulation of filamentous growth of a population of unicellular organisms GO:1900428
Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
1 Q5AKU6 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1 Q5AKU6 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH GO:1900442
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
1 Q5AKU6 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900445
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1 Q5AKU6 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P87323 (/IDA) Q07084 (/IDA) Q07084 (/IDA) Q07084 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P87323 (/HDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 P87323 (/HDA)
Mcs4 RR-MAPKKK complex GO:1990315
A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.
1 P87323 (/IDA)
Mcs4 RR-MAPKKK complex GO:1990315
A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.
1 P87323 (/IMP)
Mcs4 RR-MAPKKK complex GO:1990315
A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.
1 P87323 (/IPI)