The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Peptidase S8/S53 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Tripeptidyl peptidase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
9 P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI)
Tripeptidyl-peptidase activity GO:0008240
Catalysis of the release of an N-terminal tripeptide from a polypeptide.
9 P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
9 P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI) P29144 (/IPI)
Tripeptidyl-peptidase activity GO:0008240
Catalysis of the release of an N-terminal tripeptide from a polypeptide.
2 Q64560 (/IDA) Q9V6K1 (/IDA)
Tripeptidyl-peptidase activity GO:0008240
Catalysis of the release of an N-terminal tripeptide from a polypeptide.
1 Q64514 (/ISO)
Peptide binding GO:0042277
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
1 Q64560 (/IDA)
Peptide binding GO:0042277
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
1 Q64514 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q64514 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
10 P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) Q64560 (/TAS)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
9 P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
2 Q64560 (/IDA) Q9V6K1 (/IDA)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
1 Q64514 (/ISO)
Positive regulation of lipid storage GO:0010884
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
1 Q09541 (/IMP)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9V6K1 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
18 P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) Q5VZU9 (/IDA)
(8 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
17 P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) Q5VZU9 (/IDA)
(7 more)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
17 P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) P29144 (/IDA) Q5VZU9 (/IDA)
(7 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS) P29144 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q64514 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q64514 (/ISO)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q64514 (/ISO)