The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"alpha/beta hydrolase
".
FunFam 177: Group XV phospholipase A2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
|
1 | Q8NCC3 (/TAS) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | Q8NCC3 (/TAS) |
|
O-acyltransferase activity GO:0008374
Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.
|
1 | Q8NCC3 (/IDA) |
|
O-acyltransferase activity GO:0008374
Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.
|
1 | Q8NCC3 (/ISS) |
|
Calcium-independent phospholipase A2 activity GO:0047499
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
|
1 | Q8NCC3 (/ISS) |
|
Calcium-independent phospholipase A2 activity GO:0047499
Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
|
1 | Q8NCC3 (/TAS) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
1 | Q8NCC3 (/TAS) |
|
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
|
1 | Q8NCC3 (/IDA) |
|
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
|
1 | Q8NCC3 (/IDA) |
|
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
|
1 | Q8NCC3 (/ISS) |
|
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
1 | Q8NCC3 (/TAS) |
|
Phosphatidylcholine catabolic process GO:0034638
The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
|
1 | Q8NCC3 (/ISS) |
|
Phosphatidylethanolamine catabolic process GO:0046338
The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
1 | Q8NCC3 (/ISS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q8NCC3 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q8NCC3 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8NCC3 (/IDA) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q8NCC3 (/ISS) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q8NCC3 (/NAS) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q8NCC3 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q8NCC3 (/HDA) |