The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"alpha/beta hydrolase
".
FunFam 114: Arylacetamide deacetylase-like 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Serine hydrolase activity GO:0017171
Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
3 | P22760 (/IDA) Q8BLF1 (/IDA) Q99PG0 (/IDA) |
|
Lipase activity GO:0016298
Catalysis of the hydrolysis of a lipid or phospholipid.
|
2 | P22760 (/TAS) Q99PG0 (/TAS) |
|
Deacetylase activity GO:0019213
Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
|
2 | P22760 (/IDA) Q7M370 (/IDA) |
|
Deacetylase activity GO:0019213
Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
|
2 | Q99PG0 (/ISS) Q9QZH8 (/ISS) |
|
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
|
1 | P22760 (/TAS) |
|
Sterol esterase activity GO:0004771
Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.
|
1 | Q6PIU2 (/TAS) |
|
Triglyceride lipase activity GO:0004806
Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
|
1 | Q99PG0 (/IDA) |
|
Triglyceride lipase activity GO:0004806
Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
|
1 | P22760 (/ISS) |
|
Serine hydrolase activity GO:0017171
Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
|
1 | Q99PG0 (/ISO) |
|
Deacetylase activity GO:0019213
Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
|
1 | Q99PG0 (/ISO) |
|
Deacetylase activity GO:0019213
Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
|
1 | P22760 (/TAS) |
|
Phosphate ion binding GO:0042301
Interacting selectively and non-covalently with phosphate.
|
1 | Q8BLF1 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q8BLF1 (/IDA) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
1 | Q9QZH8 (/NAS) |
|
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
1 | Q8BLF1 (/IMP) |
|
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
1 | P22760 (/TAS) |
|
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
|
1 | Q99PG0 (/IDA) |
|
Positive regulation of triglyceride catabolic process GO:0010898
Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
|
1 | P22760 (/ISS) |
|
Low-density lipoprotein particle clearance GO:0034383
The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
|
1 | Q6PIU2 (/TAS) |
|
SMAD protein signal transduction GO:0060395
The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.
|
1 | Q8BLF1 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
3 | P22760 (/IDA) Q7M370 (/IDA) Q99PG0 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | Q99PG0 (/ISS) Q9QZH8 (/ISS) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | P22760 (/TAS) Q6PIU2 (/TAS) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q99PG0 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q6PIU2 (/HDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q8BLF1 (/IDA) |