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CATH Superfamily 3.40.50.170

Formyl transferase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Formyl transferase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methionyl-tRNA formyltransferase. [EC: 2.1.2.9]
10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).
    		 934 A0A023PBA1 A0A026V8S4 A0A029HHI0 A0A029IK90 A0A037YAZ9 A0A062FS35 A0A069XLF8 A0A070FDY8 A0A070UJ88 A0A072X853
    (924 more...)
    Formyltetrahydrofolate deformylase. [EC: 3.5.1.10]
    10-formyltetrahydrofolate + H(2)O = formate + tetrahydrofolate.
      		 170 A0A026V812 A0A029I4E1 A0A029IWC8 A0A037YFU4 A0A063XBI3 A0A069XI07 A0A070FHN7 A0A070SJH8 A0A070UGU4 A0A073FBH8
      (160 more...)
      Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
      10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
        		 73 A0A024L010 A0A045IXB2 A0A069XKT2 A0A070SRF3 A0A0D6HU21 A0A0E1AF19 A0A0E1LZZ1 A0A0E1X6Q9 A0A0H2XHN0 A0A0H3KC25
        (63 more...)
        Formyltetrahydrofolate dehydrogenase. [EC: 1.5.1.6]
        10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
          		 8 O75891 P28037 Q3SY69 Q5RFM9 Q63ZT8 Q6GNL7 Q8K009 Q8R0Y6
          Phosphoribosylformylglycinamidine cyclo-ligase. [EC: 6.3.3.1]
          ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
            		 7 P00967 P16340 P21872 P22102 Q26255 Q59A32 Q64737
            Phosphoribosylamine--glycine ligase. [EC: 6.3.4.13]
            ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)- (5-phospho-D-ribosyl)glycinamide.
            • Formerly EC 6.3.1.3.
            		 7 P00967 P16340 P21872 P22102 Q26255 Q59A32 Q64737