The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Vaccinia Virus protein VP39
".
FunFam 333: Histone-lysine N-methyltransferase, H3 lysine-79 s...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone-lysine N-methyltransferase activity GO:0018024
Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
|
2 | Q4GZF2 (/IDA) Q4GZF2 (/IDA) |
|
Histone-lysine N-methyltransferase activity GO:0018024
Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
|
1 | Q4QD41 (/ISO) |
|
Histone methyltransferase activity (H3-K79 specific) GO:0031151
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein.
|
1 | Q55AX2 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Antigenic variation GO:0020033
Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.
|
2 | Q4GZF2 (/IMP) Q4GZF2 (/IMP) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
2 | Q4GZF2 (/IMP) Q4GZF2 (/IMP) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | Q55AX2 (/IMP) |
|
Antigenic variation GO:0020033
Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.
|
1 | Q4QD41 (/ISO) |
|
Regulation of sorocarp development GO:0031156
Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.
|
1 | Q55AX2 (/IMP) |
|
Histone H3-K79 methylation GO:0034729
The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.
|
1 | Q55AX2 (/IMP) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
1 | Q4QD41 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q4GZF2 (/IDA) Q4GZF2 (/IDA) Q55AX2 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q581Z0 (/EXP) Q581Z0 (/EXP) |
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
2 | Q581Z0 (/EXP) Q581Z0 (/EXP) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
2 | Q4GZF2 (/IDA) Q4GZF2 (/IDA) |
|
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
|
1 | Q4QD41 (/ISO) |