The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 275: DNA (cytosine-5)-methyltransferase 3-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9CWR8 (/IPI) Q9CWR8 (/IPI) Q9UJW3 (/IPI)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
3 Q9CWR8 (/IDA) Q9CWR8 (/IDA) Q9UJW3 (/IDA)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
2 Q9CWR8 (/ISO) Q9CWR8 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
2 Q9CWR8 (/ISO) Q9CWR8 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
2 Q9CWR8 (/ISS) Q9CWR8 (/ISS)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q9UJW3 (/ISA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q9UJW3 (/IPI)

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Placenta development GO:0001890
The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
DNA methylation GO:0006306
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
DNA methylation on cytosine GO:0032776
The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
DNA methylation on cytosine GO:0032776
The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9CWR8 (/ISO) Q9CWR8 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9CWR8 (/ISS) Q9CWR8 (/ISS)
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Stem cell differentiation GO:0048863
The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
Chorionic trophoblast cell differentiation GO:0060718
The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Genetic imprinting GO:0071514
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Negative regulation of DNA methylation GO:1905642
Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Negative regulation of DNA methylation GO:1905642
Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
Positive regulation of DNA methylation GO:1905643
Any process that activates or increases the frequency, rate or extent of DNA methylation.
2 Q9CWR8 (/IMP) Q9CWR8 (/IMP)
Positive regulation of DNA methylation GO:1905643
Any process that activates or increases the frequency, rate or extent of DNA methylation.
2 Q1LZ50 (/ISS) Q9UJW3 (/ISS)
DNA methylation GO:0006306
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
1 Q9UJW3 (/NAS)
Regulation of gene expression by genetic imprinting GO:0006349
Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself.
1 Q9UJW3 (/NAS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q9UJW3 (/NAS)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 Q1LZ50 (/IEP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9UJW3 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Condensed nuclear chromosome GO:0000794
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
2 Q9CWR8 (/IDA) Q9CWR8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9CWR8 (/IDA) Q9CWR8 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q9CWR8 (/TAS) Q9CWR8 (/TAS)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
2 Q9CWR8 (/IDA) Q9CWR8 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9CWR8 (/IDA) Q9CWR8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UJW3 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UJW3 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UJW3 (/HDA)