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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1078: Leucine carboxyl methyltransferase 1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
[Phosphatase 2A protein]-leucine-carboxy methyltransferase. [EC: 2.1.1.233]
S-adenosyl-L-methionine + [phosphatase 2A protein]-leucine = S-adenosyl- L-homocysteine + [phosphatase 2A protein]-leucine methyl ester.
  • Methylates the C-terminal leucine of phosphatase 2A.
  • A key regulator of protein phosphatase 2A.
  • The methyl ester is hydrolyzed by EC 3.1.1.89.
  • Occurs mainly in the cytoplasm, Golgi region and late endosomes.
 2 P0CO56 P0CO57