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CATH Superfamily 3.40.50.10860

Leucine Dehydrogenase, chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine Dehydrogenase, chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Bifunctional protein FolD

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methenyltetrahydrofolate cyclohydrolase. [EC: 3.5.4.9]
5,10-methenyltetrahydrofolate + H(2)O = 10-formyltetrahydrofolate.
    		 25670 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2
    (25660 more...)
    Methylenetetrahydrofolate dehydrogenase (NADP(+)). [EC: 1.5.1.5]
    5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
      		 25661 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2 A0A015S2F2
      (25651 more...)
      Methylenetetrahydrofolate dehydrogenase (NAD(+)). [EC: 1.5.1.15]
      5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
        		 9 D3YZG8 D3ZUA0 F6ZFR0 P13995 P18155 Q04448 Q0P5C2 Q5ZKA5 Q9H903