The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Crotonobetainyl-coa:carnitine coa-transferase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: succinate--hydroxymethylglutarate CoA-transferase ...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinyl-CoA--L-malate CoA-transferase. [EC: 2.8.3.22]
(1) Succinyl-CoA + (S)-malate = succinate + (S)-malyl-CoA. (2) Succinyl-CoA + (S)-citramalate = succinate + (S)-citramalyl-CoA.
  • The enzyme, purified from the bacterium Chloroflexus aurantiacus, can also accept itaconate as acceptor, with lower efficiency.
  • It is part of the 3-hydroxypropanoate cycle for carbon assimilation.
6 A9WC39 A9WC39 A9WC40 Q1KLK0 Q1KLK0 Q1KLK1
Succinate--hydroxymethylglutarate CoA-transferase. [EC: 2.8.3.13]
Succinyl-CoA + 3-hydroxy-3-methylglutarate = succinate + (S)-3-hydroxy-3- methylglutaryl-CoA.
  • Malonyl-CoA can also act as donor, more slowly.
3 Q68FU4 Q7TNE1 Q9HAC7
Succinyl-CoA--D-citramalate CoA-transferase. [EC: 2.8.3.20]
(1) Succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA. (2) Succinyl-CoA + (R)-malate = succinate + (R)-malyl-CoA.
  • The enzyme, purified from the bacterium Clostridium tetanomorphum, can also accept itaconate as acceptor, with lower efficiency.
1 A9WGE3