The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Malic enzyme, N-terminal domain
".
FunFam 5: Malic enzyme
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malate dehydrogenase (decarboxylating) (NAD+) activity GO:0004471
Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q8L7K9 (/IPI) Q9SIU0 (/IPI) Q9SIU0 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
|
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
|
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
2 | Q9SIU0 (/IEP) Q9SIU0 (/IEP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |
|
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
3 | Q8L7K9 (/IDA) Q9SIU0 (/IDA) Q9SIU0 (/IDA) |