View in Gene3D

CATH Superfamily 3.40.50.10230

Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cobalt-precorrin-8 methylmutase. [EC: 5.4.99.60]
Cobalt-precorrin-8 = cobyrinate.
  • The enzyme catalyzes the the conversion of cobalt-precorrin-8 to cobyrinate by methyl rearrangement, a step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis.
  • The equivalent enzyme in the aerobic pathway is EC 5.4.99.61.
 43 A0A0D6FID9 A0A0F6B377 A0A0F7J9J4 A0A0H3BP62 A0A0H3NN19 A0A0M0QFA0 A0A0R9PAN6 A0A0T9WE91 A0A0U1H5S5 A0A1R2ZJ39
(33 more...)
Precorrin-8X methylmutase. [EC: 5.4.99.61]
Precorrin-8X = hydrogenobyrinate.
  • The enzyme catalyzes the the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement, a step in the aerobic (late cobalt insertion) pathway of adenosylcobalamin biosynthesis.
  • The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60.
  • Formerly EC 5.4.1.2.
 22 A0A045HHC2 A0A072ZRT0 A0A0H2ZCY3 A0A0H3LAQ3 A0A0H3MBP2 A0A0T6YD03 A0A0T6YXH8 A0A109SNU3 A0A109SXP8 A0A157WTI7
(12 more...)