The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Plasma membrane ATPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
37 P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI) P0ABB8 (/IPI)
(27 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
6 P19456 (/IDA) P19456 (/IDA) P20431 (/IDA) P20431 (/IDA) P20649 (/IDA) P20649 (/IDA)
Proton-exporting ATPase activity, phosphorylative mechanism GO:0008553
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
6 P19456 (/IDA) P19456 (/IDA) P20431 (/IDA) P20431 (/IDA) P20649 (/IDA) P20649 (/IDA)
Proton-exporting ATPase activity, phosphorylative mechanism GO:0008553
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
4 Q42556 (/ISS) Q42556 (/ISS) Q9SU58 (/ISS) Q9SU58 (/ISS)
Proton-exporting ATPase activity, phosphorylative mechanism GO:0008553
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
2 Q43128 (/IGI) Q43128 (/IGI)
Proton-exporting ATPase activity, phosphorylative mechanism GO:0008553
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
2 Q43128 (/IMP) Q43128 (/IMP)
Ion transmembrane transporter activity, phosphorylative mechanism GO:0015662
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
2 Q43128 (/ISS) Q43128 (/ISS)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
2 P20649 (/IMP) P20649 (/IMP)
ATPase-coupled cation transmembrane transporter activity GO:0019829
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
2 Q43128 (/ISS) Q43128 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P54679 (/IC)
Proton-exporting ATPase activity, phosphorylative mechanism GO:0008553
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
1 P54679 (/TAS)
Magnesium ion transmembrane transporter activity GO:0015095
Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.
1 Q55EN7 (/ISS)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
1 P54679 (/IDA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
6 P19456 (/IDA) P19456 (/IDA) P20431 (/IDA) P20431 (/IDA) P20649 (/IDA) P20649 (/IDA)
Vacuole organization GO:0007033
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
2 Q43128 (/IMP) Q43128 (/IMP)
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
2 Q43128 (/IMP) Q43128 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
2 P20649 (/IMP) P20649 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q9SU58 (/IMP) Q9SU58 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
2 P20649 (/IMP) P20649 (/IMP)
Proanthocyanidin biosynthetic process GO:0010023
The chemical reactions and pathways resulting in the formation of proanthocyanidin.
2 Q43128 (/IMP) Q43128 (/IMP)
Regulation of stomatal movement GO:0010119
Any process that modulates the frequency, rate or extent of stomatal movement.
2 P20649 (/IMP) P20649 (/IMP)
Seed coat development GO:0010214
The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.
2 Q43128 (/IMP) Q43128 (/IMP)
Stomatal opening GO:1990069
The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
2 P20649 (/IMP) P20649 (/IMP)
Magnesium ion transport GO:0015693
The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q55EN7 (/ISS)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
1 P54679 (/TAS)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
46 P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA) P0ABB8 (/IDA)
(36 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
10 P20431 (/IDA) P20431 (/IDA) P20649 (/IDA) P20649 (/IDA) P54679 (/IDA) Q9LV11 (/IDA) Q9LV11 (/IDA) Q9LV11 (/IDA) Q9M2A0 (/IDA) Q9SH76 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
6 P20431 (/IDA) P20431 (/IDA) P20649 (/IDA) P20649 (/IDA) Q43128 (/IDA) Q43128 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 P19456 (/IDA) P19456 (/IDA) P20431 (/IDA) P20431 (/IDA) P20649 (/IDA) P20649 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P96271 (/HDA) P96271 (/HDA) P9WPS5 (/HDA) P9WPS5 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P96271 (/HDA) P96271 (/HDA) P9WPS5 (/HDA) P9WPS5 (/HDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
2 P9WPS5 (/HDA) P9WPS5 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P20649 (/IDA) P20649 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 P20649 (/IDA) P20649 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
2 Q42556 (/IDA) Q42556 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 P20649 (/IDA) P20649 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q42556 (/ISS) Q42556 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q43128 (/IDA) Q43128 (/IDA)
Plant-type vacuole membrane GO:0009705
The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
2 Q43128 (/IDA) Q43128 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P20649 (/ISS) P20649 (/ISS)