The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 44: CTD nuclear envelope phosphatase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
26 O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI) O95476 (/IPI)
(16 more)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
24 O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP) O95476 (/IMP)
(14 more)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
22 O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS)
(12 more)
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Nuclear envelope organization GO:0006998
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
22 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(12 more)
Nuclear envelope organization GO:0006998
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
22 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(12 more)
Mitotic nuclear envelope disassembly GO:0007077
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
22 O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS)
(12 more)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
22 O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI) O95476 (/IGI)
(12 more)
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
22 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(12 more)
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
19 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(9 more)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Nuclear envelope organization GO:0006998
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
4 Q3TP92 (/IGI) Q3TP92 (/IGI) Q3TP92 (/IGI) Q3TP92 (/IGI)
Gamete generation GO:0007276
The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
4 Q3TP92 (/IMP) Q3TP92 (/IMP) Q3TP92 (/IMP) Q3TP92 (/IMP)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
4 Q3TP92 (/IMP) Q3TP92 (/IMP) Q3TP92 (/IMP) Q3TP92 (/IMP)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
4 Q3TP92 (/IMP) Q3TP92 (/IMP) Q3TP92 (/IMP) Q3TP92 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
2 Q9VRG7 (/IMP) Q9VRG7 (/IMP)
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
2 Q9VRG7 (/IMP) Q9VRG7 (/IMP)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 Q9VRG7 (/IGI) Q9VRG7 (/IGI)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
2 Q9VRG7 (/IMP) Q9VRG7 (/IMP)
Regulation of nuclear division GO:0051783
Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
1 Q20432 (/IMP)
Head development GO:0060322
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
1 Q5U3T3 (/IGI)
Head development GO:0060322
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
1 Q5U3T3 (/IMP)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Nem1-Spo7 phosphatase complex GO:0071595
A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.
32 Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS) Q1RMV9 (/ISS)
(22 more)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
27 I3L1D9 (/IDA) I3L3K5 (/IDA) I3L4B2 (/IDA) I3L4B2 (/IDA) I3L4B2 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(17 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
26 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(16 more)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
23 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(13 more)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
22 O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS) O95476 (/TAS)
(12 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
22 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(12 more)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
22 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(12 more)
Nem1-Spo7 phosphatase complex GO:0071595
A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.
22 O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA) O95476 (/IDA)
(12 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q3TP92 (/IDA) Q3TP92 (/IDA) Q3TP92 (/IDA) Q3TP92 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)
Nem1-Spo7 phosphatase complex GO:0071595
A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.
4 Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO) Q3TP92 (/ISO)