The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: HAD family hydrolase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sorbitol-6-phosphatase. [EC: 3.1.3.50]
Sorbitol 6-phosphate + H(2)O = sorbitol + phosphate.
  • Acts, very slowly, on hexose 6-phosphates.
14562 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45
(14552 more...)
2-deoxyglucose-6-phosphatase. [EC: 3.1.3.68]
2-deoxy-D-glucose 6-phosphate + H(2)O = 2-deoxy-D-glucose + phosphate.
  • Also active toward fructose 1-phosphate.
14562 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45
(14552 more...)
Mannitol-1-phosphatase. [EC: 3.1.3.22]
D-mannitol 1-phosphate + H(2)O = D-mannitol + phosphate.
    14562 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45
    (14552 more...)
    Sugar-phosphatase. [EC: 3.1.3.23]
    Sugar phosphate + H(2)O = sugar + phosphate.
    • Has a wide specificity, acting on aldohexose 1-phosphates, ketohexose 1-phosphates, aldohexose 6-phosphates, ketohexose 6-phosphates, both phosphate ester bonds of fructose 1,6-bisphosphate, phosphoric esters of disaccharides, and on pentose and triose phosphates, but at a slower rate.
    14562 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45 A0A023YY45
    (14552 more...)