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CATH Superfamily 3.40.309.10

Aldehyde Dehydrogenase; Chain A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 31: Phenylacetic acid degradation protein MaoC

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Oxepin-CoA hydrolase. [EC: 3.3.2.12]
2-oxepin-2(3H)-ylideneacetyl-CoA + H(2)O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde.
  • The enzyme from Escherichia coli is a bifunctional fusion protein that also catalyzes EC 1.17.1.7.
  • Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway.
  • The enzyme from Escherichia coli also exhibits enoyl-CoA hydratase activity utilizing crotonyl-CoA as a substrate.
  • Formerly EC 3.7.1.16.
 420 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51
(410 more...)
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. [EC: 1.2.1.91]
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP(+) + H(2)O = 3-oxo-5,6- dehydrosuberyl-CoA + NADPH.
  • The enzyme from Escherichia coli is a bifunctional fusion protein that also catalyzes EC 3.3.2.12.
  • Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway.
  • Formerly EC 1.17.1.7.
 420 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51 A0A070VA51
(410 more...)