The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Aldehyde dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 33 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
13 E9Q3E1 (/IDA) J3QMK6 (/IDA) P30838 (/IDA) P47739 (/IDA) P47740 (/IDA) P51648 (/IDA) Q70DU8 (/IDA) Q70DU8 (/IDA) Q80VQ0 (/IDA) Q80VQ0 (/IDA)
(3 more)
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
9 P11883 (/ISS) P47739 (/ISS) Q70DU8 (/ISS) Q70DU8 (/ISS) Q70E96 (/ISS) Q70E96 (/ISS) Q70E96 (/ISS) Q8W033 (/ISS) Q8W033 (/ISS)
Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
9 P47739 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA)
3-chloroallyl aldehyde dehydrogenase activity GO:0004028
Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
6 A0A0F7RFH4 (/ISS) A0A0F7RFH4 (/ISS) Q70DU8 (/ISS) Q70DU8 (/ISS) Q8W033 (/ISS) Q8W033 (/ISS)
Long-chain-aldehyde dehydrogenase activity GO:0050061
Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.
5 P30839 (/ISS) P47740 (/ISS) Q5RF60 (/ISS) Q5RF60 (/ISS) Q60HH8 (/ISS)
Medium-chain-aldehyde dehydrogenase activity GO:0052814
Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.
5 P30839 (/ISS) P47740 (/ISS) Q5RF60 (/ISS) Q5RF60 (/ISS) Q60HH8 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P30838 (/IPI) P43353 (/IPI) P43353 (/IPI) P51648 (/IPI)
3-chloroallyl aldehyde dehydrogenase activity GO:0004028
Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
3 P11883 (/IDA) P30839 (/IDA) P47739 (/IDA)
3-chloroallyl aldehyde dehydrogenase activity GO:0004028
Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
3 P43353 (/TAS) P43353 (/TAS) P48448 (/TAS)
Aldehyde dehydrogenase [NAD(P)+] activity GO:0004030
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
3 P30838 (/TAS) P43353 (/TAS) P43353 (/TAS)
3-chloroallyl aldehyde dehydrogenase activity GO:0004028
Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
2 P47739 (/ISO) P47740 (/ISO)
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
2 P47739 (/ISO) P47740 (/ISO)
Aldehyde dehydrogenase [NAD(P)+] activity GO:0004030
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
2 P43353 (/IDA) P43353 (/IDA)
Aldehyde dehydrogenase [NAD(P)+] activity GO:0004030
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
2 Q80VQ0 (/ISO) Q80VQ0 (/ISO)
Alcohol dehydrogenase (NADP+) activity GO:0008106
Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
2 P11883 (/ISS) P47739 (/ISS)
Aldehyde dehydrogenase (NADP+) activity GO:0033721
Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.
2 Q8W033 (/IDA) Q8W033 (/IDA)
Coniferyl-aldehyde dehydrogenase activity GO:0050269
Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.
2 Q0BYG1 (/ISS) Q0BYG1 (/ISS)
3-chloroallyl aldehyde dehydrogenase activity GO:0004028
Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
1 P47739 (/IMP)
Aldehyde dehydrogenase (NAD) activity GO:0004029
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
1 P51648 (/IMP)
Aldehyde dehydrogenase [NAD(P)+] activity GO:0004030
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
1 P48448 (/EXP)
Alcohol dehydrogenase (NADP+) activity GO:0008106
Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
1 P30838 (/IDA)
Alcohol dehydrogenase (NADP+) activity GO:0008106
Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
1 P47739 (/ISO)
Benzaldehyde dehydrogenase (NAD+) activity GO:0018479
Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
1 P30838 (/IDA)
Benzaldehyde dehydrogenase (NAD+) activity GO:0018479
Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
1 P47739 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P51648 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P47740 (/ISO)
Long-chain-alcohol oxidase activity GO:0046577
Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.
1 P51648 (/IDA)
Long-chain-alcohol oxidase activity GO:0046577
Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.
1 P47740 (/ISO)
Long-chain-aldehyde dehydrogenase activity GO:0050061
Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.
1 P51648 (/IDA)
Long-chain-aldehyde dehydrogenase activity GO:0050061
Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.
1 P47740 (/ISO)
Coniferyl-aldehyde dehydrogenase activity GO:0050269
Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.
1 O86447 (/IDA)
Medium-chain-aldehyde dehydrogenase activity GO:0052814
Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.
1 P51648 (/IDA)
Medium-chain-aldehyde dehydrogenase activity GO:0052814
Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.
1 P47740 (/ISO)

There are 59 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carotenoid biosynthetic process GO:0016117
The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
8 Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA) Q2FWX9 (/IDA)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
6 E9Q3E1 (/IC) J3QMK6 (/IC) P47739 (/IC) P47740 (/IC) Q80VQ0 (/IC) Q80VQ0 (/IC)
Hexadecanal metabolic process GO:0046458
The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
5 P30839 (/ISS) P47740 (/ISS) Q5RF60 (/ISS) Q5RF60 (/ISS) Q60HH8 (/ISS)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
5 P30838 (/IDA) P43353 (/IDA) P43353 (/IDA) P51648 (/IDA) Q99PH4 (/IDA)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
4 Q70DU8 (/IEP) Q70DU8 (/IEP) Q8W033 (/IEP) Q8W033 (/IEP)
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
4 P43353 (/TAS) P43353 (/TAS) P48448 (/TAS) P51648 (/TAS)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
4 P47739 (/ISO) P47740 (/ISO) Q80VQ0 (/ISO) Q80VQ0 (/ISO)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
3 P43353 (/TAS) P43353 (/TAS) P48448 (/TAS)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
3 P43353 (/TAS) P43353 (/TAS) P48448 (/TAS)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
2 P30838 (/IDA) P51648 (/IDA)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
2 P47739 (/ISO) P47740 (/ISO)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
2 P11883 (/ISS) P47739 (/ISS)
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
2 A0A0F7RFH4 (/ISS) A0A0F7RFH4 (/ISS)
Response to desiccation GO:0009269
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
2 Q70DU8 (/IEP) Q70DU8 (/IEP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
2 Q8W033 (/IEP) Q8W033 (/IEP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q70DU8 (/IEP) Q70DU8 (/IEP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P43353 (/IDA) P43353 (/IDA)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q80VQ0 (/ISO) Q80VQ0 (/ISO)
Eugenol metabolic process GO:0042854
The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
2 Q0BYG1 (/ISS) Q0BYG1 (/ISS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
2 P43353 (/TAS) P43353 (/TAS)
Aldehyde catabolic process GO:0046185
The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.
2 P43353 (/IDA) P43353 (/IDA)
Aldehyde catabolic process GO:0046185
The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.
2 Q80VQ0 (/ISO) Q80VQ0 (/ISO)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 P11883 (/ISS) P47739 (/ISS)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 P30839 (/IDA)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 P47740 (/ISO)
Fatty acid alpha-oxidation GO:0001561
A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
1 P51648 (/TAS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P11883 (/IDA)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P47739 (/ISO)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
1 P51648 (/NAS)
Sesquiterpenoid metabolic process GO:0006714
The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.
1 P47740 (/ISO)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 P30838 (/TAS)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 P51648 (/IMP)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 P47740 (/ISO)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
1 P51648 (/IMP)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
1 P47740 (/ISO)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P11883 (/IEP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 P11883 (/IEP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P11883 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P47739 (/ISO)
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
1 P51648 (/IMP)
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
1 P47740 (/ISO)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P11883 (/IDA)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P11883 (/IEP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P47739 (/ISO)
Phytol metabolic process GO:0033306
The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
1 Q99PH4 (/IDA)
Phytol metabolic process GO:0033306
The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
1 P51648 (/IMP)
Phytol metabolic process GO:0033306
The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
1 P47740 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P11883 (/IDA)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P11883 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P47739 (/ISO)
Eugenol catabolic process GO:0042856
The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
1 O86447 (/IDA)
Formaldehyde metabolic process GO:0046292
The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
1 P30839 (/IDA)
Formaldehyde metabolic process GO:0046292
The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
1 P47740 (/ISO)
Hexadecanal metabolic process GO:0046458
The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
1 P51648 (/IDA)
Hexadecanal metabolic process GO:0046458
The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
1 P47740 (/ISO)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
1 P11883 (/IDA)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
1 P47739 (/ISO)
Response to cAMP GO:0051591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 P11883 (/IDA)
Response to cAMP GO:0051591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 P47739 (/ISO)

There are 39 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
8 P30838 (/IDA) P30839 (/IDA) P47740 (/IDA) Q70DU8 (/IDA) Q70DU8 (/IDA) Q70E96 (/IDA) Q70E96 (/IDA) Q70E96 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 J3QMK6 (/IDA) P11883 (/IDA) P43353 (/IDA) P43353 (/IDA) P47739 (/IDA) Q80VQ0 (/IDA) Q80VQ0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 I3L3I9 (/IDA) P11883 (/IDA) P30838 (/IDA) P30839 (/IDA) Q80VQ0 (/IDA) Q80VQ0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 I3L3I9 (/IDA) J3QMK6 (/IDA) P30838 (/IDA) Q80VQ0 (/IDA) Q80VQ0 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 Q70DU8 (/IDA) Q70DU8 (/IDA) Q70E96 (/IDA) Q70E96 (/IDA) Q70E96 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
4 Q70DU8 (/ISS) Q70DU8 (/ISS) Q8W033 (/ISS) Q8W033 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P47739 (/ISO) Q80VQ0 (/ISO) Q80VQ0 (/ISO)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 Q70DU8 (/IDA) Q70DU8 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 P47739 (/ISO) P47740 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 Q70DU8 (/IDA) Q70DU8 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P47739 (/ISO) P47740 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P30838 (/ISS) P47739 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P43353 (/TAS) P43353 (/TAS)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q70DU8 (/IDA) Q70DU8 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q8W033 (/IDA) Q8W033 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 Q8W033 (/IDA) Q8W033 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P47739 (/IDA) P47740 (/IDA)
Secretory granule membrane GO:0030667
The lipid bilayer surrounding a secretory granule.
2 P43353 (/TAS) P43353 (/TAS)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
2 P43353 (/HDA) P43353 (/HDA)
Specific granule membrane GO:0035579
The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
2 P43353 (/TAS) P43353 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P43353 (/HDA) P43353 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P30838 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P30839 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P47740 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P47739 (/NAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P47740 (/HDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 P47740 (/HDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 P47740 (/ISO)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
1 Q99PH4 (/IDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
1 P51648 (/TAS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 P51648 (/TAS)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
1 E9Q3E1 (/IDA)
Lipid droplet GO:0005811
An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
1 P48448 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P30838 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P47739 (/ISO)
Extrinsic component of endoplasmic reticulum membrane GO:0042406
The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 P30839 (/IDA)
Extrinsic component of endoplasmic reticulum membrane GO:0042406
The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 P47740 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P51648 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P47740 (/ISO)