The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Thioredoxin-dependent thiol peroxidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
175 P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA)
(165 more)
Hydroperoxide reductase activity GO:0032843
Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.
175 P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA)
(165 more)
Peroxiredoxin activity GO:0051920
Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
1 Q2RSQ7 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
175 P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP) P0AE52 (/IMP)
(165 more)
Glutamine biosynthetic process GO:0006542
The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.
1 Q2RSQ7 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
175 P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA) P0AE52 (/IDA)
(165 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA) P9WIE1 (/HDA)
(1 more)