The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 56: Thiol peroxidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
133 P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI) P0A862 (/IPI)
(123 more)
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
131 P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA)
(121 more)
Hydroperoxide reductase activity GO:0032843
Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.
122 P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA)
(112 more)
Peroxidase activity GO:0004601
Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Peroxiredoxin activity GO:0051920
Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
122 P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP) P0A862 (/IMP)
(112 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Response to nitrosative stress GO:0051409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Evasion or tolerance by symbiont of host-produced nitric oxide GO:0052060
The process in which an organism avoids the effects of nitric oxide produced as a defense response by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
11 P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS)
(1 more)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
11 P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA) P9WG35 (/IDA)
(1 more)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
9 P57668 (/IMP) P57668 (/IMP) P57668 (/IMP) P57668 (/IMP) P57668 (/IMP) P57668 (/IMP) P57668 (/IMP) P57668 (/IMP) P57668 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
122 P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA)
(112 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
122 P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA) P0A862 (/IDA)
(112 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
11 P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA)
(1 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA) P9WG35 (/HDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS) P9WG35 (/TAS)
(1 more)