The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: NADH-quinone oxidoreductase subunit E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
180 P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI) P0AFD1 (/IPI)
(170 more)
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
180 P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP)
(170 more)
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
180 P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS) P0AFD1 (/ISS)
(170 more)
Ferredoxin hydrogenase activity GO:0008901
Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
4 Q3Z860 (/ISS) Q3Z860 (/ISS) Q3Z8I3 (/ISS) Q3Z9A9 (/ISS)
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
4 Q3Z860 (/ISS) Q3Z860 (/ISS) Q3Z8I3 (/ISS) Q3Z9A9 (/ISS)
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
2 Q74GA4 (/ISS) Q74GA4 (/ISS)
Hydrogen dehydrogenase (NADP+) activity GO:0050583
Catalysis of the reaction: NADP+ + H2 = NADPH + H+.
2 Q46505 (/IDA) Q46505 (/IDA)
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
2 Q46505 (/IDA) Q46505 (/IDA)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
2 Q74GA4 (/ISS) Q74GA4 (/ISS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
180 P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA)
(170 more)
NADH dehydrogenase complex GO:0030964
An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
180 P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA)
(170 more)
Plasma membrane respiratory chain complex I GO:0045272
A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.
180 P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA) P0AFD1 (/IDA)
(170 more)
Plasma membrane respiratory chain complex I GO:0045272
A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.
180 P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP) P0AFD1 (/IMP)
(170 more)
Ferredoxin hydrogenase complex GO:0009375
An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.
4 Q3Z860 (/ISS) Q3Z860 (/ISS) Q3Z8I3 (/ISS) Q3Z9A9 (/ISS)