The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Blast:Protein SCO1 homolog, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
14 P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P38072 (/IDA) P38072 (/IDA) P38072 (/IDA) P38072 (/IDA)
(4 more)
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
5 A6H784 (/ISS) Q5RH02 (/ISS) Q8VCL2 (/ISS) Q9VMX4 (/ISS) Q9VMX4 (/ISS)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
3 Q38EA7 (/ISA) Q38EA7 (/ISA) Q38FS2 (/ISA)
Copper chaperone activity GO:0016531
Directly binding to and delivering copper ions to a target protein.
3 O42899 (/ISS) Q9VMX4 (/ISS) Q9VMX4 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O43819 (/IPI) O75880 (/IPI)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 O43819 (/NAS)
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
1 O43819 (/IDA)
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
1 Q8VCL2 (/ISO)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
12 P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P38072 (/IGI) P38072 (/IGI) P38072 (/IGI) P38072 (/IGI)
(2 more)
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
12 P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P23833 (/IGI) P38072 (/IGI) P38072 (/IGI) P38072 (/IGI) P38072 (/IGI)
(2 more)
Mitochondrial respiratory chain complex IV assembly GO:0033617
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
11 O43819 (/IMP) O75880 (/IMP) P23833 (/IMP) P23833 (/IMP) P23833 (/IMP) P23833 (/IMP) P23833 (/IMP) P23833 (/IMP) Q5SUC9 (/IMP) Q8VYP0 (/IMP)
(1 more)
Mitochondrial respiratory chain complex IV assembly GO:0033617
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
6 A1A4J8 (/ISS) A6H784 (/ISS) O42899 (/ISS) Q5RH02 (/ISS) Q5SUC9 (/ISS) Q8VCL2 (/ISS)
Copper ion homeostasis GO:0055070
Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
3 Q8LAL0 (/IMP) Q8LAL0 (/IMP) Q8VCL2 (/IMP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
2 Q5RH02 (/ISS) Q8VCL2 (/ISS)
Respiratory chain complex IV assembly GO:0008535
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
2 Q38EA7 (/ISA) Q38EA7 (/ISA)
Respiratory chain complex IV assembly GO:0008535
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
2 Q9VMX4 (/ISS) Q9VMX4 (/ISS)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q8VYP0 (/IMP) Q8VYP0 (/IMP)
Cytochrome complex assembly GO:0017004
The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
2 Q9VMX4 (/IMP) Q9VMX4 (/IMP)
Mitochondrial respiratory chain complex IV assembly GO:0033617
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
2 Q5SUC9 (/ISO) Q8VCL2 (/ISO)
Positive regulation of ATP biosynthetic process GO:2001171
Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.
2 Q9VMX4 (/IMP) Q9VMX4 (/IMP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1 O43819 (/IMP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1 Q8VCL2 (/ISO)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q8VCL2 (/IMP)
Muscle system process GO:0003012
A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
1 Q8VCL2 (/IMP)
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O42899 (/ISS)
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
1 Q5SUC9 (/IMP)
Respiratory chain complex IV assembly GO:0008535
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
1 Q8VCL2 (/IMP)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
1 Q8VCL2 (/IMP)
Respiratory electron transport chain GO:0022904
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
1 Q8VCL2 (/IMP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 O43819 (/TAS)
Negative regulation of proteasomal protein catabolic process GO:1901799
Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
1 Q5SUC9 (/IMP)

There are 26 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
13 P23833 (/HDA) P23833 (/HDA) P23833 (/HDA) P23833 (/HDA) P23833 (/HDA) P23833 (/HDA) P38072 (/HDA) P38072 (/HDA) P38072 (/HDA) P38072 (/HDA)
(3 more)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
6 P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P23833 (/IDA) P23833 (/IDA)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
6 P38072 (/IDA) P38072 (/IDA) P38072 (/IDA) P38072 (/IDA) P38072 (/IDA) P38072 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 O43819 (/IDA) Q5SUC9 (/IDA) Q8VCL2 (/IDA) Q8VYP0 (/IDA) Q8VYP0 (/IDA)
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 A1A4J8 (/ISS) A6H784 (/ISS) Q5RH02 (/ISS) Q5SUC9 (/ISS) Q8VCL2 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q38EA7 (/IDA) Q38EA7 (/IDA) Q38FS2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O97196 (/ISO) Q4Q8Z5 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q38EA7 (/ISM) Q38EA7 (/ISM)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9VMX4 (/ISS) Q9VMX4 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q38EA7 (/RCA) Q38EA7 (/RCA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O43819 (/TAS) O75880 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 A0A1D8PTX2 (/IDA) A0A1D8PTX2 (/IDA)
Myofibril GO:0030016
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
2 O43819 (/IDA) O75880 (/IDA)
Myofibril GO:0030016
The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
2 Q5SUC9 (/ISO) Q8VCL2 (/ISO)
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 O43819 (/IDA) O75880 (/IDA)
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q5SUC9 (/ISO) Q8VCL2 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8VCL2 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 O42899 (/ISS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q38FS2 (/RCA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 O43819 (/TAS)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q38FS2 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q4Q8Z5 (/ISO)
Host cell mitochondrial intermembrane space GO:0072492
The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.
1 O75880 (/IDA)
Host cell mitochondrial intermembrane space GO:0072492
The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.
1 Q5SUC9 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q38FS2 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4Q8Z5 (/ISO)