The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Severin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: Coactosin-like 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
22 C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA) C7G537 (/IDA)
(12 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q14019 (/IPI) Q14019 (/IPI) Q14019 (/IPI) Q9CQI6 (/IPI) Q9CQI6 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
5 Q14019 (/IPI) Q14019 (/IPI) Q14019 (/IPI) Q9CQI6 (/IPI) Q9CQI6 (/IPI)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q9CQI6 (/ISO) Q9CQI6 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
2 Q9CQI6 (/ISO) Q9CQI6 (/ISO)
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
1 P34121 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neural crest cell migration GO:0001755
The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
17 C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP)
(7 more)
Actin filament polymerization GO:0030041
Assembly of actin filaments by the addition of actin monomers to a filament.
17 C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP) C7G537 (/IMP)
(7 more)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
3 Q14019 (/TAS) Q14019 (/TAS) Q14019 (/TAS)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
2 Q9CQI6 (/IDA) Q9CQI6 (/IDA)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 P34121 (/HEP)
Regulation of actin filament polymerization GO:0030833
Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
1 P34121 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
4 P34121 (/HDA) Q75JY8 (/HDA) Q75JY8 (/HDA) Q75JY8 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 Q14019 (/TAS) Q14019 (/TAS) Q14019 (/TAS)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
3 Q75JY8 (/HDA) Q75JY8 (/HDA) Q75JY8 (/HDA)
Secretory granule lumen GO:0034774
The volume enclosed by the membrane of a secretory granule.
3 Q14019 (/TAS) Q14019 (/TAS) Q14019 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 Q14019 (/HDA) Q14019 (/HDA) Q14019 (/HDA)
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
3 Q14019 (/TAS) Q14019 (/TAS) Q14019 (/TAS)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
1 P34121 (/IC)