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CATH Superfamily 3.40.1380.20

Pyruvate kinase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pyruvate kinase, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pyruvate kinase. [EC: 2.7.1.40]
ATP + pyruvate = ADP + phosphoenolpyruvate.
  • UTP, GTP, CTP, ITP and dATP can also act as donors.
  • Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
 605 A0A023YXG5 A0A023YZ04 A0A024SM32 A0A025CPH7 A0A025CSP1 A0A026UEW2 A0A028AKX7 A0A028AV41 A0A028E4W5 A0A028EAK7
(595 more...)
Diadenylate cyclase. [EC: 2.7.7.85]
2 ATP = 2 diphosphate + cyclic di-3',5'-adenylate.
  • Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signaling molecule.
  • The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity.
 1 Q58408