The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Acetylglutamate kinase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 19: Uridylate kinase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
UMP kinase. [EC: 2.7.4.22]
ATP + UMP = ADP + UDP.
  • Strictly specific for UMP as substrate and is used by prokaryotes in the de novo synthesis of pyrimidines, in contrast to eukaryotes, which use the dual-specificity enzyme EC 2.7.4.14 for the same purpose.
  • Subject of feedback regulation, being inhibited by UTP and activated by GTP.
612 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65 A0A0B7LH65
(602 more...)