The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NADH Oxidase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Nitroreductase family

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor GO:0016657
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.
8 Q96VH4 (/ISS) Q96VH4 (/ISS) Q96VH4 (/ISS) Q96VH4 (/ISS) Q96VH4 (/ISS) Q96VH4 (/ISS) Q96VH4 (/ISS) Q96VH4 (/ISS)
Oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor GO:0016657
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.
5 P37261 (/IDA) P37261 (/IDA) P37261 (/IDA) P37261 (/IDA) P37261 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P37261 (/IGI) P37261 (/IGI) P37261 (/IGI) P37261 (/IGI) P37261 (/IGI)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P37261 (/IMP) P37261 (/IMP) P37261 (/IMP) P37261 (/IMP) P37261 (/IMP)
Negative regulation of fatty acid metabolic process GO:0045922
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
5 P37261 (/IMP) P37261 (/IMP) P37261 (/IMP) P37261 (/IMP) P37261 (/IMP)
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
4 Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YA8 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 P37261 (/HDA) P37261 (/HDA) P37261 (/HDA) P37261 (/HDA) P37261 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA)
(3 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 P37261 (/HDA) P37261 (/HDA) P37261 (/HDA) P37261 (/HDA) P37261 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA) Q96VH4 (/HDA)
(3 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YB2 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
5 Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YA8 (/IDA) Q57YB2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q0H8 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4Q0H8 (/ISO)