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CATH Superfamily 3.30.990.10

Formiminotransferase, N-terminal subdomain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Formiminotransferase, N-terminal subdomain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamate formimidoyltransferase. [EC: 2.1.2.5]
5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.
  • In eukaryotes occurs as a bifunctional enzyme also having EC 4.3.1.4 activity.
  • Formerly EC 2.1.2.6.
 10 J7M4D7 O88618 O95954 P53603 Q54JL3 Q6KZM5 Q91XD4 Q99XR4 Q9HI69 Q9YH58
Formimidoyltetrahydrofolate cyclodeaminase. [EC: 4.3.1.4]
5-formimidoyltetrahydrofolate = 5,10-methenyltetrahydrofolate + NH(3).
  • In eukaroytes, occurs as a bifunctional enzyme that also has EC 2.1.2.5 activity.
 6 O88618 O95954 P53603 Q54JL3 Q91XD4 Q9YH58
5-formyltetrahydrofolate cyclo-ligase. [EC: 6.3.3.2]
ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10- methenyltetrahydrofolate.
    		 4 J7M4D7 Q6KZM5 Q99XR4 Q9HI69