The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Frataxin/CyaY
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Mitochondrial chaperone Frataxin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferroxidase activity GO:0004322
Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI)
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Iron chaperone activity GO:0034986
Directly binding to and delivering iron ions to a target protein.
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Iron chaperone activity GO:0034986
Directly binding to and delivering iron ions to a target protein.
9 Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
9 Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
9 Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP)
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
9 Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
9 Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
9 Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
9 Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP)
Response to iron(II) ion GO:0010040
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.
9 Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
9 Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI) Q07540 (/IGI)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
9 Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP) Q07540 (/IMP)
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
9 Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI) Q07540 (/IPI)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA) Q07540 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
9 Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
9 Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
9 Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA) Q07540 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
9 Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS) Q07540 (/TAS)